Two-dimensional liquid chromatography
Enhancement of automation efficiency：End-to-end integration: pre-processing, separation, testing, and data processing all completed with a single click.Online SPE Technology: Blood sample pretreatment reduced from several hours to 10 minutes, minimizing errors and contamination.
Sensitivity breakthrough in detection：Multidimensional orthogonal separation: Elimination of matrix interference results in clearer peak profiles for low-abundance compounds.Online enrichment: Concentrates trace components by dozens of times, achieving a detection limit as low as the nanogram (ng) level.
The separation index has increased exponentially:Dual separation mechanism: The peak capacity is 5-10 times higher than that of one-dimensional analysis.Precision central cutting: Targeted separation of the target substance to resolve peak overlap issues
Detection Stability Assurance:Full automation: Minimizes human error and enhances the reproducibility of results.Reliable long-term performance: The standard curve remains stable for>6 months, ensuring precise and reliable results.
List of Detectable Drugs (Partial)
Antipsychotic drugs (used to treat schizophrenia and bipolar disorder).
Olanzapine, Clozapine, Nortropanol, Quetiapine, Desethylquetiapine, Risperidone, Paliperidone, Chlorpromazine, Aripiprazole, Dehydroaripiprazole, Ziracuron, Amisulpride, Sulpiride, Perphenazine, Haloperidol, Paroxetine...
Antidepressants (for the treatment of depression and other mood disorders)
Mirtazapine, Citalopram, Nortriptyramine, Eszitalopram, Paroxetine, Duloxetine, Sertraline, Nortsertraline, Fluvoxamine, Doxepin, Clomipramine, Amitriptyline, Nortamitriptyline, Venlafaxine, Nortvenlafaxine, Fluoxetine, Nortfluoxetine...
Antiepileptic drugs (for the prevention and treatment of epileptic seizures)
Valproate, carbamazepine, phenytoin, phenobarbital, oxcarbazepine, levetiracetam, lamotrigine. ....
Antineoplastic agents (for the treatment of malignant tumors)
Methotrexate, Fluorouracil, Paclitaxel, Docetaxel, Imatinib, Apatinib, Enotinib, Icotinib, Gefitinib, Sunitinib, Desethylsunitinib, Osimertinib, Anlotinib, Dasatinib...
Antibiotics (for treating severe drug-resistant bacterial infections)
Vancomycin, Norvancomycin, Tencanidine, Tigecycline, Meropenem, Imipenem, Cefotaxime, Gentamicin...
Antifungal agents (for the treatment of invasive fungal infections)
Fluconazole, voriconazole, daptomycin, posaconazole, amphotericin B, itraconazole, trimethoprim, sulfamethoxazole, caspofungin, sulbactam, moxifloxacin, ofloxacin, cefoperazone, linezolid, sulfapyridine. ......
Immunosuppressants (which inhibit abnormal immune responses)
Cyclosporine, Tacrolimus, Sirolimus, Everolimus, Mycophenolate Mofetil
Antituberculosis drugs (for the treatment and prevention of tuberculosis)
Pyrazinamide, Rifampicin, Rifapentine, Isoniazid
Lipid-soluble vitamins (support growth and development, regulate immunity)
Vitamin A, 25-hydroxyvitamin D2, 25-hydroxyvitamin D3, Vitamin E
Hwatime 2D Solution
Conventional chromatography used for TDM issues.
Kit Information
Detection method: Two-dimensional liquid chromatography (2D-LC)
Kit specifications: 48-person/box, 96-person/box, 192-person/box
Product advantages: high specificity, high sensitivity, high method integration efficiency, rapid processing speed, strong compatibility, and durable standard curves.
Pre-treatment process:
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